One day after the an donut (fried donut filled with bean paste) which Jin had conceived as a confection to treat beriberi had created a sensation in Edo, he is asked by Matsumoto Ryojun of the Institute of Western Medicine and also the doctor to the shogun, to present the donut to Princess Kazunomiya, who is suspected to have beriberi. It is a big honour. But while Saki and the others at Jinyudo are overcome with joy, Jin broods alone as he has qualms that it could change history again … Meanwhile, Jin is reunited with Nokaze, who was driven out of her tenement house and is seeking a job. Concerned for Nokaze, he encourages her to work at Jinyudo. Saki who has been managing the financially troubled Jinyudo also cheerfully welcomes Nokaze. Jin later decides to present the donut. Accompanied by Saki, he visits Princess Kazunomiya, who has travelled incognito to watch Sawamura Tanosuke’s play. He presents it to her without incident, and is relieved to see her eat it as if it was delicious. However, that is short-lived as Princess Kazunomiya suddenly collapses on the spot … (thetvdb.com)