Time passes … On a day, two years since Minakata Jin went back in time to the closing days of the Tokugawa shogunate in the Edo era, Jin visits Saki’s family home after noticing that she has been looking down. He is told by her older brother, Kyotaro, that their mother, Sakae has beriberi (a nervous system ailment caused by a deficiency of vitamin B1) . According to Kyotaro, Saki, who has been worried about their mother’s health, had visited the Tachibana residence a few days ago and advised Sakae to consult a doctor. However, Sakae would not even allow Saki to set foot in the Tachibana house and turned her away because she still has not forgiven Saki for breaking off her engagement. Hoping to help Sakae in some way, Jin attempts to administer treatment by making a kind of confection since she loves sweets, but … … At that moment, Sakamoto Ryoma comes up from Kyoto to enlist Jin’s help. Katsu Kaishu’s mentor, Sakuma Shozan, had sustained injuries in an attack by the Shinsengumi and is on the verge of death. Jin goes to Kyoto with Ryoma as he agonises whether he will radically alter history by saving an important person who will have an influence on the period. There, he sees Shozan who is so seriously injured that it would be a miracle if he lives. Shozan somehow escapes death through Jin’s frantic treatment and perseverance. Then Shozan regains consciousness, and shocking words come out from his mouth … …! After that, Jin remains in Kyoto and concentrates on treating people injured in the war between the Choshu and Satsuma domains. One day, he is taken away to some place by the Shinsengumi who appear out of nowhere. Jin has been brought to the residence of Saigo Takamori in Satsuma domain. Saigo is suffering from appendicitis and needs to be operated on immediately or his life will be in danger … … (thetvdb.com)